Abstract
For diversifying the role and requirements of pesticides, chemical structures of new pesticides must become larger or more complex with multiple chirality. Thus, natural products and their derivatives have increasingly become the source for new pesticide design. Several routes for generating chiral synthons based on asymmetric synthesis or from natural products have well been illustrated in the literature. However, limited access to chiral raw natural products and economic synthesis routes is the key reason why single enantiomers are less common than they might be. A perspective approach to produce chiral synthons from biomass feedstocks is proposed as a highly promising route for producing enantiomerically pure pesticides. The use of chiral synthons has been implied in the design of synthesis routes for new chiral pesticides. Thus, chiral compounds from biomass feedstocks can be used to produce enantiomerically pure pesticides. Chiral building blocks and their derivatives can be used in a variety of ways in the development of new chiral pesticides, and biorefining technologies will accelerate their development. The use of chiral synthons derived from biomass feedstocks can also be expected to reduce CO2 to combat climate change.
Figures & Tables
Fig. 1. Agrochemical market composition (A), distribution (B), and chiral pesticide (C).
